Monday, June 24, 2013

BacterioFiles Special Edition - ASM2013 General Meeting Day 4

Presenting my poster
Here's my summary of the fourth and final day of ASM2013, with a special surprise guest appearance at the end!

Session 1: Synthetic Genomics to Create a Minimal Bacterial Cell and Some Other Neat Stuff
Presented by John I. Glass
He talked about the cell with the synthetic genome (full episode 13), and about how important it is to determine what is the minimal amount of genome a cell needs to grow--knowing that, you can start there and build almost anything you want.
He also talked about a new method of producing new flu strains for vaccine production using synthetic nucleic acids, which could greatly shorten the time it takes to get a new vaccine going to counter a pandemic.

Session 2: C. difficile vs. the Microbiota: The Enemy of My Enemy is My Friend
Presented by Shonna McBride
When a probiotic (Lactococcus lactis) was grown with C. difficile, the latter was killed.

Session 3: An Intriguing Bacterial Symbiont in the Nucleus of Amoebae
Presented by Frederik Schulz
Interactions between amoebae and bacteria are interesting and also relevant to our health, considering the similarities between amoebae and cells of our immune system. This interaction is particularly interesting: bacteria living inside the nucleus.

Download Episode (5.5 MB, 6 minutes)

Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

Subscribe at iTunes, check out the show at Twitter, MicrobeWorld, or Facebook

Monday, June 17, 2013

BacterioFiles Special Edition - ASM2013 General Meeting Day 3

Here's my summary of the third day of ASM2013, wherein I met with neat people and ideas.

Session 1: Microbe-Microbe Interactions - Cell Contact-Dependent Outer Membrane Exchange in Myxobacteria
Presented by Dan Wall
Myxobacteria are super cool, a fascinating example of complex cooperative behavior in relatively simple single-celled organisms. They swarm around eating other bacteria until they get low on food, at which point they gather together to form reproductive structures called fruiting bodies to spread to new environments.
As part of the mechanism they use to coordinate their activity and distinguish between friends and foes, they seem to exchange components of their outer membrane, but only with closely-related strains.

Poster: 1485 - Understanding the Syntrophic Metabolism of a Bacterial Co-culture for Hydrogen Production
(Combination of Clostridium cellulolyticum and Rhodopseudomonas palustris to convert cellulosic plant material into hydrogen)
Y. Jiao, A. Navid, B. Stewart, J. McKinlay, M. Thelen, J. Pett-Ridge

Poster: 1702 - Non-Photosynthetic, Deep-Branching Cyanobacteria of the Human Gut and Subsurface Permit Inference of the Cyanobacterial Ancestor
S.C. Di Rienzi, I. Sharon, K.C. Wrighton, O. Koren, L.A. Hug, B.C. Thomas, J.K. Goodrich, J.T. Bell, T.D. Spector, J.F. Banfield, R.E. Ley

They started out talking about scientific misconduct with Ferric Fang, then with Andrew Camilli about the virus with a CRISPR system (listen at about 1 hour 2 min in to hear my question!), and also with Suzanne Fleiszig and Michelle Swanson about a gruesome-sounding eye infection and defenses against intracellular bacteria. You should give it a listen (or watch)!


Download Episode (4.3 MB, 4.6 minutes)

Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

Subscribe at iTunes, check out the show at Twitter, MicrobeWorld, or Facebook