Monday, June 25, 2018

BacterioFiles 344 - Bacteriophages Bypass Body Barriers

Cell culture setup
Nguyen et al, 2017,
mBio 8:e01874-17
This episode: Phages may be passing through the barriers in our body all the time!

Thanks to Dr. Jeremy Barr for his contribution!
Download Episode (13.2 MB, 14.5 minutes)

Show notes:
Microbe of the episode: Rhodobacter virus RcCronus

News item

Journal Paper:
Nguyen S, Baker K, Padman BS, Patwa R, Dunstan RA, Weston TA, Schlosser K, Bailey B, Lithgow T, Lazarou M, Luque A, Rohwer F, Blumberg RS, Barr JJ. 2017. Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers. mBio 8:e01874-17.

Other interesting stories:
  • Yeast species uses same codon for two different amino acids (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Sunday, June 17, 2018

    BacterioFiles 343 - Super Cells Save Susceptible Species

    Deinococcus radiodurans
    This episode: Very radiation-resistant bacteria can protect other, less-resistant microbes from some of the effects of chronic radiation!

    Download Episode (9.7 MB, 10.6 minutes)

    Show notes:
    Microbe of the episode: Paramecium bursaria Chlorella virus CA4A

    News item

    Journal Paper:
    Shuryak I, Matrosova VY, Gaidamakova EK, Tkavc R, Grichenko O, Klimenkova P, Volpe RP, Daly MJ. 2017. Microbial cells can cooperate to resist high-level chronic ionizing radiation. PLOS ONE 12:e0189261.

    Other interesting stories:
  • Panda gut microbes help them detoxify cyanide in their diet (paper)
  • Modified probiotics can detect and inhibit cholera in baby mice

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, June 11, 2018

    BacterioFiles 342 - Cyanide Stops Cell Suckers

    Chromobacterium growing on agar
    This episode: Some bacteria can defend themselves from bacterial predators by producing cyanide!

    Thanks to Dr. Robert Mitchell for his contribution!

    Download Episode (7.7 MB, 8.4 minutes)

    Show notes:
    Microbe of the episode: Dyoepsilonpapillomavirus 1

    News item

    Journal Paper:
    Mun W, Kwon H, Im H, Choi SY, Monnappa AK, Mitchell RJ. 2017. Cyanide Production by Chromobacterium piscinae Shields It from Bdellovibrio bacteriovorus HD100 Predation. mBio 8:e01370-17.

    Other interesting stories:
  • Using bacterial DNA to estimate movement of river water
  • Making bacteria produce biologic drugs that last longer in the body
  • Fungal pigment could be a useful semiconductor
  • Parasitic microbe uses chemical defense against defenses of fungus-growing ants

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, June 4, 2018

    BacterioFiles 341 - Cancer Killer Could Cure Cryptic Contagion

    HIV particles on infected cell
    By Liza Gross,
    PLOS Biology 2006, e445
    CC BY 2.5
    This episode: A virus designed to target cancer could also help eliminate hidden HIV infections!

    Thanks to Nischal Ranganath for his contribution!

    Download Episode (8.7 MB, 9.5 minutes)

    Show notes:
    Microbe of the episode: Streptomyces pluricolorescens

    News item

    Journal Paper:
    Ranganath N, Sandstrom TS, Schinkel B, C S, Côté SC, Angel JB. 2018. The Oncolytic Virus MG1 Targets and Eliminates Cells Latently Infected With HIV-1: Implications for an HIV Cure. J Infect Dis 217:721–730.

    Other interesting stories:
  • Gut microbes could affect immune defense against liver cancer

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline: