Sunday, April 22, 2018

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Monday, April 16, 2018

BacterioFiles 336 - Phages Fortify Friendly Fighters

Neutrophil captures Pseudomonas
aeruginosa
cells
By Paulo Henrique Orlandi Mourao,
CC BY-SA 3.0
This episode: Phage therapy can work very well when combined with an effective immune response from the host!

Download Episode (12.9 MB, 14.1 minutes)

Show notes:
Microbe of the episode: Gammapapillomavirus 8

News item about "nightmare bacteria"

Journal Paper:
Roach DR, Leung CY, Henry M, Morello E, Singh D, Di Santo JP, Weitz JS, Debarbieux L. 2017. Synergy between the Host Immune System and Bacteriophage Is Essential for Successful Phage Therapy against an Acute Respiratory Pathogen. Cell Host Microbe 22:38-47.e4.

Other interesting stories:
  • Bacteria make antibacterial silver nanoparticles (paper)
  • Bacteria produce chemical that could enhance effectiveness of penicillin
  • Engineering yeast to produce valuable complex chemicals
  • Specific types of gut microbes affect cancer treatment effectiveness
  • Microbe-produced enzymes could help clean oil spills

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, April 9, 2018

    BacterioFiles 335 - Purported Paraprobiotic Potential

    Lactobacillus bacteria
    Pelzer et al. 2012
    PLOS One e49965
    This episode: Paraprobiotics, or killed probiotic bacteria, are studied for health effects, but results and study design are questionable!

    Download Episode (11.5 MB, 12.6 minutes)

    Show notes:
    Microbe of the episode: Phlox virus S

    Journal Paper:
    Nishida K, Sawada D, Kawai T, Kuwano Y, Fujiwara S, Rokutan K. 2017. Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality. J Appl Microbiol 123:1561–1570.

    Other interesting stories:
  • Parasites infecting ants hide their presence
  • Inoculating soybean crops with extra bacteria can help them fix more nitrogen
  • Microbes help mice recover from bone marrow transplant (paper)
  • Lots of drugs other than antibiotics can harm gut communities (paper)
  • Using biofilm as camera film, for imaging

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: iTunes, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, April 2, 2018

    BacterioFiles 334 - Measuring Mycelial Moth Muncher Management

    Gypsy moth caterpillar
    By CharlesC, CC BY-SA 4.0
    This episode: Figuring out the best way to study the spread of a fungus that kills an invasive tree-eating caterpillar pest!

    Download Episode (8.2 MB, 8.9 minutes)

    Show notes:
    Microbe of the episode: Pasteurella aerogenes

    News item

    Journal Paper:
    Bittner TD, Hajek AE, Liebhold AM, Thistle H. 2017. Modification of a Pollen Trap Design To Capture Airborne Conidia of Entomophaga maimaiga and Detection of Conidia by Quantitative PCR. Appl Environ Microbiol 83:e00724-17.

    Other interesting stories:

  • Studying the whale microbiome
  • Gut bacteria help herbivorous ants get enough nitrogen
  • Environment factors can affect our microbes apart from genetic factors
  • Fiber could encourage gut microbes to help with type 2 diabetes
  • Gut microbes can affect parasitic worm infections

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: iTunes, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline: