Sunday, May 27, 2018

BacterioFiles 340 - Plasmid Promotes Plant Pathogenesis

Pathogenic Rhodococcus causing
disfigurement
From: Savory et al, eLife 6:e30925
This episode: Some bacteria living around plants can become pathogenic just by gaining a few genes!

Thanks to Skylar Fuller for her contribution!

Download Episode (9.4 MB, 10.3 minutes)

Show notes:
Microbe of the episode: Alternanthera yellow vein betasatellite

News item

Journal Paper:
Savory EA, Fuller SL, Weisberg AJ, Thomas WJ, Gordon MI, Stevens DM, Creason AL, Belcher MS, Serdani M, Wiseman MS, Gr├╝nwald NJ, Putnam ML, Chang JH. 2017. Evolutionary transitions between beneficial and phytopathogenic Rhodococcus challenge disease management. eLife 6:e30925.

Other interesting stories:
  • More gut microbe diversity could be good for arteries
  • Human gut microbes have enzymes that break down specific plant toxins (paper)
  • Gut microbes ferment fiber and modify immune response to protect mice from flu
  • Cooperation of plants and fungi breaks down if one finds alternative lifestyle (paper)
  • Disproven "arsenic in the DNA" bacterium actually has interesting arsenic detox strategies (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, May 21, 2018

    BacterioFiles 339 - Medical Microbiota Measurement

    Clostridium difficile bacteria
    This episode: Fecal microbiota transplants work just as well when taken in pill form as when delivered through a tube!

    Download Episode (10.5 MB, 11.5 minutes)

    Show notes:
    Microbe of the episode: Halobacterium halobium

    News item

    Journal Paper:
    Kao D, Roach B, Silva M, Beck P, Rioux K, Kaplan GG, Chang H-J, Coward S, Goodman KJ, Xu H, Madsen K, Mason A, Wong GK-S, Jovel J, Patterson J, Louie T. 2017. Effect of Oral Capsule- vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial. J Am Med Assoc 318:1985–1993.

    Other interesting stories:
  • Protein that can form prions important for protecting mice from influenza (paper)
  • Figuring out how bacteria in fruit flies kill only males
  • Healthy skin microbes could help treat eczema
  • Good gut microbe is very comfortable with immune system
  • Archaea in bogs could be good microbes for plants too (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, May 14, 2018

    BacterioFiles 338 - Maverick Mouse Microbes Mitigate Maladies

    House mouse,
    Mus musculus domesticus
    This episode: Gut microbe transplants from wild mice protect lab mice from disease!

    Download Episode (9.8 MB, 10.7 minutes)

    Show notes:
    Microbe of the episode: Cabassou virus

    News item

    Journal Paper:
    Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B. 2017. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance. Cell 171:1015-1028.e13.

    Other interesting stories:
  • Phage cocktail can eliminate pathogen with minimal collateral damage
  • Preventive probiotics given with antibiotics can help keep C. diff away
  • Early exposure to dust and bacteria linked with less immune response to stress
  • Viruses that help wasps parasitize caterpillars also inhibit plant defenses
  • Only one microbe species can live in extremely acidic, almost boiling lake

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline: