Monday, July 23, 2018

BacterioFiles 348 - Huge Host Hackers Have Historic Histones

Marseillevirus
By: Swiss Institute of Bioinformatics
This episode: Giant viruses produce DNA-packing proteins that seem to have branched off from eukaryotes far back in evolutionary history!

Download Episode (6 MB, 6.5 minutes)

Show notes:
Microbe of the episode: Caulobacter maris

News item

Journal Paper:
Erives AJ. 2017. Phylogenetic analysis of the core histone doublet and DNA topo II genes of Marseilleviridae: evidence of proto-eukaryotic provenance. Epigenetics & Chromatin 10:55.

Other interesting stories:
  • Swimming bacteria can affect liquid viscosity, to the point of superfluidity
  • Tiny soil roundworms can sense and avoid pathogens by their gases
  • Beetle bacterium makes defensive compound with genes taken from an ocean microbe

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, July 16, 2018

    BacterioFiles 347 - Adenovirus Adapter Allows Assignment

    Virus and shielded virus
    Schmid et al, 2018, Nat Commun
    This episode: Adding adapters to anti-cancer virus helps it avoid destruction by the body so it can target the tumors!

    Thanks to Dr. Andreas Pl├╝ckthun for his contribution!

    Download Episode (7.8 MB, 8.5 minutes)

    Show notes:
    Microbe of the episode: Tomato leaf curl Vietnam virus

    News item

    Journal Paper:
    Schmid M, Ernst P, Honegger A, Suomalainen M, Zimmermann M, Braun L, Stauffer S, Thom C, Dreier B, Eibauer M, Kipar A, Vogel V, Greber UF, Medalia O, Pl├╝ckthun A. 2018. Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun 9:450.

    Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, July 9, 2018

    BacterioFiles 346 - Prokaryote Prey Plug Picoalgae

    Alga (C) with bacterial prey (P)
    By: Kamennaya et al,
    PLOS Biol 2018
    This episode: Very small ocean algae consume bacterial prey of a similar size to themselves by engulfing them only partially!

    Download Episode (8.9 MB, 9.7 minutes)

    Show notes:
    Microbe of the episode: Bradyrhizobium japonicum

    Journal Paper:
    Kamennaya NA, Kennaway G, Fuchs BM, Zubkov MV. 2018. “Pomacytosis”—Semi-extracellular phagocytosis of cyanobacteria by the smallest marine algae. PLOS Biol 16:e2003502.

    Other interesting stories:

  • Using nanomagnets to control quorum sensing by pulling bacteria together (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline:

    Monday, July 2, 2018

    BacterioFiles 345 - Super Sonic Cell Sacs

    Anabaena flos-aquae,
    a source for gas vesicle genes
    This episode: Protein bags of gas in bacteria could help make ultrasound imaging more versatile!

    Download Episode (7.6 MB, 8.25 minutes)

    Show notes:
    Microbe of the episode: Cronobacter virus Esp2949-1

    News item

    Journal Paper:
    Bourdeau RW, Lee-Gosselin A, Lakshmanan A, Farhadi A, Kumar SR, Nety SP, Shapiro MG. 2018. Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts. Nature 553:86–90.

    Other interesting stories:
  • Laxatives shown very disruptive to gut microbes in mice
  • Evidence not good that probiotics can reduce anxiety in people

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook.

    Episode outline: