Monday, February 20, 2017

BacterioFiles 287 - Producing Potent Pathogen Prophylaxes

Streptococcus pneumoniae
Credit: CDC/M.S. Mitchell
This episode: Polymer-coated bacteria make really good vaccines!

Download Episode (9.2 MB, 10 minutes)

Show notes:
News item

Journal Paper:
Li Y, Beitelshees M, Fang L, Hill A, Ahmadi MK, Chen M, Davidson BA, Knight P, Smith RJ, Andreadis ST, Hakansson AP, Jones CH, Pfeifer BA. 2016. In situ pneumococcal vaccine production and delivery through a hybrid biological-biomaterial vector. Sci Adv 2:e1600264.

Other interesting stories:
  • Fiber stops microbes from eating protective gut mucus
  • Potential new antibiotics predicted and discovered in human microbes
  • Bacteria communicate to work together against viruses
  • Root bacteria help protect plants against arsenic and infections
  • Fungus helps plants defend themselves against roundworms

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

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    Monday, February 13, 2017

    BacterioFiles 286 - Prokaryote Prevents Pregnancy Pathogen

    This episode: Bacteria in mosquito cells can block transmission of Zika virus!

    Download Episode (8.1 MB, 8.9 minutes)

    Show notes:
    News item

    Journal Paper:
    Aliota MT, Peinado SA, Velez ID, Osorio JE. 2016. The wMel strain of Wolbachia Reduces Transmission of Zika virus by Aedes aegypti. Sci Rep 6:28792.

    Other interesting stories:
  • Modified bacteria change behavior as temperature changes
  • Ants' bacteria produce antifungal compounds (paper)
  • Gut microbes may be related to macular degeneration
  • E. coli could be used to make vaccines (paper)
  • Using bacteria to produce testosterone (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

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    Monday, February 6, 2017

    BacterioFiles 285 - Sultry Snow Cell Sun Screen

    Red snow
    By Will Beback, CC BY-SA 3.0
    This episode: Algae growing in Arctic snow make red pigments that heat up their surroundings!

    Download Episode (6.8 MB, 7.5 minutes)

    Show notes:
    News item

    Journal Paper:
    Lutz S, Anesio AM, Raiswell R, Edwards A, Newton RJ, Gill F, Benning LG. 2016. The biogeography of red snow microbiomes and their role in melting arctic glaciers. Nat Commun 7:11968.

    Other interesting stories:
  • Bacterial species benefit from losing genes they don't need
  • Soil fungi help plants grow better in salty conditions (paper)
  • Bacterial predators actually help treat infection in rats
  • Some bacteria produce methane while harvesting phosphorus (paper)
  • Probiotics could help treat skin problems (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

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    Monday, January 30, 2017

    BacterioFiles 284 - Remedies Reduce Recipient Rejection

    This episode: Modifying mice's microbial communities increased mouse survival before a transplantation was rejected by their immune system!
    Download Episode (9.6 MB, 10.5 minutes)

    Show notes:
    News item

    Journal Paper:
    Lei YM, Chen L, Wang Y, Stefka AT, Molinero LL, Theriault B, Aquino-Michaels K, Sivan AS, Nagler CR, Gajewski TF, Chong AS, Bartman C, Alegre M-L. 2016. The composition of the microbiota modulates allograft rejection. J Clin Invest 126:2736–2744.

    Other interesting stories:
  • CRISPR system can be used to record info in cells (paper)
  • The history of beer yeasts
  • Bacteria could help treat citrus tree disease (paper)
  • Some viruses bud off from Archaea like in eukaryotes (paper)
  • Infant microbe communities different with vs. without eczema (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

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    Monday, January 23, 2017

    BacterioFiles 283 - Phages Furnish Photosynthetic Fortifications

    Nostoc
    By YAMAMAYA, CC BY-SA 3.0
    This episode: Viruses infecting photosynthetic bacteria could transfer immunity to other viruses between their hosts!
    Download Episode (6.8 MB, 7.4 minutes)

    Show notes:
    News item

    Journal Paper:
    Chénard C, Wirth JF, Suttle CA. 2016. Viruses Infecting a Freshwater Filamentous Cyanobacterium (Nostoc sp.) Encode a Functional CRISPR Array and a Proteobacterial DNA Polymerase B. mBio 7:e00667-16.

    Other interesting stories:
  • Salt-loving bacteria could maintain concrete structures in the ocean (paper)
  • Ancient viral infection changed how mammals develop placentas and muscle
  • Bees and flowers trade microbes
  • Fungi have specific genes that help trees with drought
  • Probiotic can affect Candida yeast's virulence (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

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    Monday, January 16, 2017

    BacterioFiles 282 - Mycobacteria Make Mice Mellow

    Elevated plus-maze
    By Bd008 - Own work
    CC BY-SA 3.0
    This episode: Vaccinating mice with heat-killed soil bacteria reduced their stressed behavior and inflammation!
    Download Episode (9.8 MB, 10.7 minutes)

    Show notes:
    Journal Paper:
    Reber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, Füchsl AM, Langgartner D, Walker FR, Hale MW, Perez GL, Treuren WV, González A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CA. 2016. Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci 113:E3130–E3139.

    Other interesting stories:
  • Art with glowing bacteria
  • Making good bacterial tumor killers (paper)
  • It's worth considering plants' microbes in addition to their genes (review)
  • Virus affects how bees are attracted to plants
  • Finding new biofuels algae in wastewater (paper)

  • Post questions or comments here or email to bacteriofiles@gmail.com. Thanks for listening!

    Subscribe at iTunes or Google Play, support the show at Patreon, or check out the show at Twitter, or Facebook

    Monday, January 9, 2017